June 3 - Morgan Llwyd, Welsh Puritan preacher and writer (b. 1619)
October 8 - Jean de Quen, French Jesuit missionary
February 11 - The assault on Copenhagen by Swedish forces is beaten back with heavy losses.
May 25 - Richard Cromwell resigns as Lord Protector of England following the restoration of the Long Parliament, beginning a second brief period of the republican government called the Commonwealth of England.
June 29 - The Russians, led by prince Trubetskoy are defeated by the Ukrainian armies of Ivan Vyhovsky in the Battle of Konotop.
November 17 - Peace of the Pyrenees is signed between France and Spain.
December 8 - Mexican border town Ciudad Juárez is founded by Fray García de San Francisco.