January 28 - Horace Walpole, in a letter to Horace Mann, coins the word serendipity.
May 28 - French and Indian War: in the first engagement of the war, Virginia militia under 22-year-old Lieutenant Colonel George Washington defeat a French reconnaissance party in the Battle of Jumonville Glen in what is now Fayette County in southwestern Pennsylvania.
July 3 - French and Indian War: George Washington surrenders Fort Necessity to French forces.
July 4 - French and Indian War: George Washington surrenders Fort Necessity to French Capt. Louis Coulon de Villiers.