July 22 - Marie François Xavier Bichat, French anatomist (b. 1771)
September 24 - Alexander Radishchev, Russian writer (b. 1749)
November 16 - André Michaux, French botanist (b. 1746)
Events
March 16 - The United States Military Academy at West Point is established.
March 25 - The Treaty of Amiens is signed as a "Definitive Treaty of Peace" between France and the Kingdom of Great Britain and Ireland.
March 28 - Heinrich Wilhelm Matthäus Olbers discovers 2 Pallas, the second asteroid known to man.
April 15 - William Wordsworth and his sister, Dorothy see a "long belt" of daffodils, inspiring the former to pen I Wandered Lonely as a Cloud.
April 26 - Napoleon Bonaparte signs a general amnesty to allow all but about one thousand of the most notorious émigrés of the French Revolution to return to France, as part of a reconciliary gesture with the factions of the Ancien Regime and to eventually consolidate his own rule.
May 3 - Washington, D.C. is incorporated as a city.
May 19 - The Légion d'Honneur is founded by Napoleon Bonaparte.
June 4 - Grieving over the death of his wife, Marie Clotilde of France, King Charles Emmanuel IV of Sardinia abdicates his throne in favor of his brother, Victor Emmanuel.
July 4 - At West Point, New York the United States Military Academy opens.
September 11 - France annexes the Kingdom of Piedmont.
November 1 - Delegates meet at Chillicothe, Ohio to form a state constitutional convention.