July 1 - Jemima Wilkinson, American preacher (b. 1752)
October 6 - Charles Emmanuel IV of Sardinia, (b. 1751)
December 5 - Count Friedrich Leopold zu Stolberg, German poet (b. 1750)
Events
February 6 - Sir Thomas Stamford Raffles founds Singapore.
February 7 - Sir Thomas Stamford Raffles leaves Singapore after just taking it over, leaving it in the hands of William Farquhar.
February 17 - The United States House of Representatives passes the Missouri Compromise.
February 19 - British explorer William Smith discovers the South Shetland Islands, and claims them in the name of King George III.
February 22 - By the Adams-Onís Treaty, Spain sells Florida to the United States for five million U.S. dollars.
May 22 - The SS Savannah leaves port at Savannah, Georgia, United States, on a voyage to become the first steamship to cross the Atlantic Ocean. The ship arrived at Liverpool, England on June 20.
June 20 - The U.S. vessel SS Savannah arrives at Liverpool, United Kingdom. She is the first steam-propelled vessel to cross the Atlantic, although most of the journey was made under sail.
July 3 - The first savings bank in the United States (The Bank of Savings in New York City) opens.
August 6 - Norwich University is founded in Vermont as the first private military school in the United States.
August 7 - Simón Bolívar triumphs over Spain in the Battle of Boyacá.
August 16 - Seventeen people die and over 600 are injured by cavalry charges at the Peterloo Massacre at a public meeting at St. Peter's Field, Manchester, England.
December 14 - Alabama becomes the 22nd U.S. state.
December 17 - Simón Bolívar declares the independence of the Republic of Gran Colombia in Angostura (now Ciudad Bolívar in Venezuela).
