June 1 - Jean Frédéric Oberlin, Alsatian pastor (b. 1740)
June 3 - Nikolai Mikhailovich Karamzin, Russian writer (b. 1766)
June 5 - Carl Maria von Weber, German composer (b. 1786)
July 4 - Thomas Jefferson 3rd President of the United States, (b. 1743)
Events
January 24 - Mississippi College is founded in Clinton, becoming the first college in the state of Mississippi.
January 30 - The Menai Suspension Bridge, considered the world's first modern suspension bridge, connecting the Isle of Anglesey to the north West coast of Wales is opened.
February 11 - University College London is founded under the name University of London.
February 24 - The signing of the Treaty of Yandaboo marks the end of the First Burmese War.
April 1 - Samuel Morey patents the internal combustion engine.
April 10 - The 10,500 inhabitants of the Greek town Messolonghi start leaving the town after a year's siege by Turkish forces. Very few of them survive.
May 22 - The HMS Beagle departs on its first voyage.
June 21 - Maniots defeat Egyptians under Ibrahim Pasha in the Battle of Vergas.
October 7 - Granite Railway (first chartered railway in the U.S.) begins operations.
November 25 - The Greek frigate Hellas arrives in Nafplion to become the first flagship of the Hellenic Navy.
December 1 - French philhellene Fabvier forces his way through the Turkish cordon and ascends the Acropolis of Athens, which had been under siege.
December 16 - Benjamin W. Edwards rides into Mexican controlled Nacogdoches, Texas and declares himself ruler of the Republic of Fredonia.