September 13 - Marie von Ebner-Eschenbach, Austrian writer (d. 1916)
October 10 - Queen Isabella II of Spain, (d. 1904)
December 5 - Christina Rossetti, English poet (d. 1894)
December 10 - Emily Dickinson, American poet (d. 1886)
December 17 - Jules de Goncourt, French publisher (d. 1870)
December 31 - Alexander Smith, Scottish poet (d. 1867)
Deaths
June 1 - Sahajanand Swami, believed to be an incarnation of god by his followers
September 15 - William Huskisson, first rail fatality (b. 1770)
September 18 - William Hazlitt, English essayist (b. 1778)
December 8 - Benjamin Constant, Swiss writer (b. 1767)
December 9 - Heinrich Christian Friedrich Schumacher, Danish surgeon
December 17 - Simón Bolívar, Venezuelan-born libertator
Events
January 13 - The Great fire of New Orleans, Louisiana begins.
February 3 - The sovereignty of Greece was confirmed in a London Protocol.
March 10 - The KNIL also known as the Royal Netherlands East Indies Army is created.
March 26 - The Book of Mormon is published in Palmyra, New York.
April 6 - The Church of Jesus Christ of Latter-day Saints is organized by Joseph Smith, Jr. and others at Fayette, New York.
May 3 - The Canterbury and Whitstable Railway is opened. It is the first steam hauled passenger railway to issue season tickets and include a tunnel.
May 13 - Ecuador gains its independence from Gran Colombia.
May 24 - "Mary Had a Little Lamb" by Sarah Josepha Hale is published.
May 24 - The first revenue trains in the United States begin service on the Baltimore and Ohio Rail Road between Baltimore, Maryland and Ellicott's Mills, Maryland.
May 26 - The Indian Removal Act is passed by the U.S. Congress; it is signed into law by President Andrew Jackson two days later.
May 28 - President Andrew Jackson signs The Indian Removal Act which relocates Native Americans.
June 12 - Beginning of the French colonization of Algeria: 34,000 French soldiers land 27 kilometers west of Algiers, at Sidi Ferruch.
July 13 - The General Assembly's Institution, now the Scottish Church College, one of the pioneering institutions that ushered the Bengal Renaissance, is founded by Alexander Duff and Raja Ram Mohan Roy, in Calcutta, India.