November 11 - Nat Turner, American slave rebel (b. 1800)
November 14 - Ignaz Pleyel, Austrian-born French composer
February 14 - Ras Marye of Yejju marches into Tigray and defeats and kills Dejazmach Sabagadis in the Battle of Debre Abbay.
February 24 - The Treaty of Dancing Rabbit Creek, the first removal treaty in accordance with the Indian Removal Act, is proclaimed. The Choctaws in Mississippi cede land east of the river in exchange for payment and land in the West.
March 10 - The French Foreign Legion is established by King Louis-Philippe to support his war in Algeria.
March 29 - Great Bosnian uprising: Bosniak rebel against Turkey.
April 14 - Soldiers marching on a bridge in Manchester, England cause it to collapse.
June 1 - James Clark Ross discovers the North Magnetic Pole.
July 21 - Inauguration of Léopold I of Belgium, first king of the Belgians.
August 21 - Nat Turner leads black slaves and free blacks in a rebellion.
August 22 - Nat Turner's slave rebellion commences just after midnight in Southampton, Virginia, leading to the deaths of more than 50 whites and several hundred African Americans who were killed in retaliation for the uprising.
August 24 - Charles Darwin is asked to travel on HMS Beagle.
August 29 - Michael Faraday discovers electromagnetic induction.
September 8 - William IV is crowned King of Great Britain.
September 15 - The locomotive John Bull operates for the first time in New Jersey on the Camden and Amboy Railroad.